The effect of chronic lithium treatment on hippocampal progenitor cells: Transcriptomic analysis and systems pharmacology.
Mina JahandidehErfan EbrahimiMohammad Hosein FarzaeiEbrahim BarzegariPublished in: Brain and behavior (2023)
As shown by gene ontology results, these findings conclude that lithium may increase the size of the hippocampus in bipolar patients by stimulating the generation of new neurons and promoting their differentiation into neuroblasts, neurons, or microglia.
Keyphrases
- end stage renal disease
- spinal cord
- newly diagnosed
- ejection fraction
- chronic kidney disease
- bipolar disorder
- peritoneal dialysis
- prognostic factors
- inflammatory response
- genome wide
- cerebral ischemia
- copy number
- solid state
- patient reported outcomes
- spinal cord injury
- blood brain barrier
- transcription factor
- patient reported