Preoperative Drug Monitoring in Management of Patients with Hip Fracture on Treatment with Direct Oral Anticoagulants.
Carlo RostagnoGiulio Maria MannarinoAlessandro CarteiGaia RubbieriAlice CeccofiglioAnna Maria GoriRoberto CivininiRossella MarcucciPublished in: Clinical interventions in aging (2024)
DOAC assay in patients with hip fracture may be useful for correct definition of time to surgery, particularly in patients who are candidates for neuraxial anesthesia. Two-thirds of patients with DOAC levels <50 ng/mL at 48 hours from last drug intake underwent uneventful neuraxial anesthesia, saving at least 24 hours in comparison to guidelines.
Keyphrases
- hip fracture
- direct oral anticoagulants
- venous thromboembolism
- atrial fibrillation
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ejection fraction
- peritoneal dialysis
- prognostic factors
- patients undergoing
- high throughput
- acute coronary syndrome
- clinical practice
- patient reported outcomes
- electronic health record
- drug induced
- adverse drug