Pediatric systemic lupus erythematosus patients in South Africa have high prevalence and severity of cardiac and vascular manifestations.
Michael J HarrisonLiesl J ZühlkeLaura B LewandowskiChristiaan ScottPublished in: Pediatric rheumatology online journal (2019)
Cardiac and vascular involvement were highly prevalent in this South African cohort. The mortality rate was high, and severe manifestations were frequent. Prospective research is needed to improve knowledge of pediatric SLE in Africa and to improve outcomes for this high-risk population.
Keyphrases
- systemic lupus erythematosus
- south africa
- end stage renal disease
- disease activity
- risk factors
- left ventricular
- ejection fraction
- chronic kidney disease
- healthcare
- newly diagnosed
- patient reported outcomes
- metabolic syndrome
- coronary artery disease
- rheumatoid arthritis
- cardiovascular disease
- adipose tissue
- hiv infected
- glycemic control