Manifestations of HbSE sickle cell disease: a systematic review.

Ibrahim KhameesFateen AtaHassan ChoudryAshraf T SolimanVincenzo De SanctisMohamed A Yassin

Published in: Journal of translational medicine (2021)

HBSE is a rare genotypic variant of SCD. It has been considered a benign form; however, there are multiple reports of severe complications. Severe complications observed in HBSE disease include vaso-occlusive crisis, acute chest syndrome, stroke, bone marrow embolism, and death.

Keyphrases

sickle cell disease
bone marrow
drug induced
early onset
risk factors
liver failure
public health
atrial fibrillation
mesenchymal stem cells
adverse drug
intensive care unit