Elevated cerebrospinal fluid neuronal injury biomarkers within 24 hours of onset in infection-triggered acute encephalopathy compared to complex febrile seizures.
Shizuka OikawaHiroshi YamaguchiMasahiro NishiyamaTatsuhito ItoAoi KawamuraTomohiro SameshimaKento SomaTakuya UedaShoichi TokumotoYusuke IshidaHiroshi KurosawaKandai NozuAzusa MaruyamaRyojiro TanakaHiroaki NagasePublished in: Journal of the neurological sciences (2024)
The elevation of S100B suggests that activated astrocytes may be closely associated with the early pathology of AESD. Elevated GDF-15 levels in infection-triggered AE suggest the activation of defense mechanisms caused by stronger neurological injury.