Dysregulated immunity in SARS-CoV-2 infected pregnant women.
Morgan L ShererJun LeiPatrick CreisherMinyoung JangRamya ReddyKristin VoegtlineSarah OlsonKirsten LittlefieldHan-Sol ParkRebecca L UrsinAbhinaya GanesanTheresa BoyerDiane M BrownSamantha N WalchAnnukka A R AntarYukari C ManabeKimberly Jones-BeattyWilliam Christopher GoldenAndrew J SatinJeanne S SheffieldAndrew S PekoszSabra L KleinIrina BurdPublished in: medRxiv : the preprint server for health sciences (2020)
SARS-CoV-2 infection during pregnancy was characterized by placental inflammation and reduced antiviral antibody responses, which may impact the efficacy of COVID-19 therapeutics in pregnancy. The long-term implications of placental inflammation for neonatal health also requires greater consideration.