Cilostazol against 2,4,6-trinitrobenzene sulfonic acid-induced colitis: Effect on tight junction, inflammation, and apoptosis.

Hiba A Al-KishaliMai A Abd El FattahWaleed A MohammadHanan S El-Abhar

Published in: JGH open : an open access journal of gastroenterology and hepatology (2019)

CS protected the colon against TNBS through its anti-inflammatory and antiapoptotic effects along with maintaining cellular tight junctions (TJs). Furthermore, CS can be beneficial as an add-on drug with the conventional treatments of colitis.

Keyphrases

oxidative stress
blood brain barrier
anti inflammatory
endoplasmic reticulum stress
cell death
cell cycle arrest
single molecule
signaling pathway
electronic health record