Ruling out lupus anticoagulants with mixing test-specific cutoff assessment and the index of circulating anticoagulant.

Published in: Research and practice in thrombosis and haemostasis (2019)

The data indicate that MTC has a tendency to generate not-corrected mixing tests in factor-deficient, warfarin, and other inhibitor samples, while ICA exhibited higher specificity. When we perform the mixing test and interpret the data, it is important to understand the characteristics of the indexes for maximizing the diagnostic potential of mixing test.

Keyphrases

atrial fibrillation
electronic health record
venous thromboembolism
big data
rheumatoid arthritis
disease activity
direct oral anticoagulants
machine learning
deep learning