Tauroursodeoxycholic acid attenuates colitis-associated colon cancer by inhibiting nuclear factor kappaB signaling.

Young Hoon KimJee Hyun KimByeong Gwan KimKook Lae LeeJi Won KimSeong-Joon Koh

Published in: Journal of gastroenterology and hepatology (2018)

These results demonstrated that TUDCA suppresses NF-κB signaling and ameliorates colitis-associated tumorigenesis, suggesting that TUDCA could be a potential treatment for CAC.

Keyphrases

nuclear factor
signaling pathway
toll like receptor
ulcerative colitis
pi k akt
mouse model
inflammatory response
climate change
human health
combination therapy
replacement therapy
smoking cessation