Diagnostic radiology and diagnostic pathology are medical disciplines that use a variety of morphological analyses with different macroscopic and microscopic resolutions for diagnosis and staging of cancers. In the clinical setting, radiology and pathology departments are often spatially separated. However, there are examples of increasingly tight cooperation and convergence, for example in the setting of multidisciplinary tumor boards. This article focuses exemplarily on the correlations of radiological and histopathological diagnostics in pancreatic cancer.