Matrix-assisted ionization mass spectrometry in targeted protein analysis - An initial evaluation.
Øystein SkjærvøSarah TrimpinTrine Grønhaug HalvorsenPublished in: Rapid communications in mass spectrometry : RCM (2019)
The results demonstrate that MAI-SRM-MS has promising potential in targeted protein determination by the bottom-up approach because of its simplicity, ease of use, and speed. However, more data is needed to confirm the results prior to application in a clinical setting.
Keyphrases
- mass spectrometry
- gas chromatography
- cancer therapy
- protein protein
- liquid chromatography
- multiple sclerosis
- amino acid
- binding protein
- electronic health record
- ms ms
- high performance liquid chromatography
- capillary electrophoresis
- small molecule
- big data
- machine learning
- risk assessment
- climate change
- tandem mass spectrometry