Selective drug deposition in lungs through pulmonary drug delivery system for effective management of drug-resistant TB.
Kaksha SankheTabassum KhanChintan BhavsarMunira MominAbdelwahab OmriPublished in: Expert opinion on drug delivery (2019)
Poor patient adherence to treatment due to side effects and extended therapeutic regimen leads to drug-resistant TB. Thus, it is essential to design novel strategies this issue by developing new chemical entities and/or new delivery systems for delivery to the lungs, consequently reducing the side effects, the frequency and the duration of treatment. Delivery of drugs to enhance the efficacy of new/existing anti-TB drugs to overcome the resistance and enhance patient compliance is underway.