Epithelial Membrane Protein 2 (EMP2) Blockade Attenuates Pathological Neovascularization in Murine Oxygen-Induced Retinopathy.

Brian AguirreMeng-Chin LinEduardo AraujoCheng-Hsiang LuDavid CaseroMichel SunSteven NusinowitzJustin HansonKara CalkinsLynn GordonMadhuri WadehraAlison Chu

Published in: Investigative ophthalmology & visual science (2024)

Our results suggest that EMP2 blockade could be a local and specific treatment modality for retinal neovascularization in oxygen-induced retinopathies, without systemic adverse effects.

Keyphrases

diabetic retinopathy
high glucose
diabetic rats
drug induced
optical coherence tomography
optic nerve