Electroconvulsive Therapy and Extracellular Matrix Glycoproteins in Patients with Depressive Episodes.

Özge Atay Canbek Murat İlhan Atagün Ozlem Devrim Balaban Derya Ipekcioglu Baris Alpugan Suat Yalcin Almila Senat Nesrin Karamustafalioglu Mehmet Cem Ilnem Ozcan Erel

Published in: Psychiatry and clinical psychopharmacology (2021)

Our results did not support the claim suggesting a possible mechanism for modulation of ECM glycoproteins by ECT. Serum levels may not necessarily reflect conformational changes in the ECM. Further studies are needed to investigate the effects of ECT on ECM glycoproteins. Modulation of the ECM may provide a new window suggesting improvement in treatments.

Keyphrases

extracellular matrix
bipolar disorder
molecular dynamics
molecular dynamics simulations
single molecule