High B3GALT5 expression confers poor clinical outcome and contributes to tumor progression and metastasis in breast cancer.

Yu-Mei LiaoYa-Hui WangJung-Tung HungYu-Ju LinYen-Lin HuangGuo-Shiou LiaoYa-Ling HsuJen-Chien WuAlice Lin-Tsing Yu

Published in: Breast cancer research : BCR (2021)

Our results demonstrated the value of B3GALT5 as a prognostic marker of breast cancer, especially among the early stage patients, and its crucial roles in regulating EMT, cell migration, and stemness thereby promoting breast cancer progression.

Keyphrases

cell migration
early stage
epithelial mesenchymal transition
stem cells
ejection fraction
newly diagnosed
prognostic factors
squamous cell carcinoma
breast cancer risk
radiation therapy
lymph node
sentinel lymph node
patient reported outcomes
neoadjuvant chemotherapy
rectal cancer