Brain SPECT perfusion and PET metabolism as discordant biomarkers in major depressive disorder.

Maud TastevinLaurent BoyerTheo KorchiaGuillaume FondChristophe LançonRaphaëlle RichieriEric Guedj

Published in: EJNMMI research (2020)

This preliminary study demonstrates more significant results with brain perfusion compared with glucose metabolism in treatment-resistant MDD, highlighting the value of brain SPECT despite less favourable instrumentation detection compared to PET.

Keyphrases

major depressive disorder
pet ct
resting state
white matter
bipolar disorder
functional connectivity
computed tomography
contrast enhanced
brain injury
loop mediated isothermal amplification
quantum dots
sensitive detection