Royal-jelly-based apitherapy can attenuate damages to male reproductive parameter following nicotine administration.

Mahsa Nazar-Zadeh Cyrus Jalili Amene Nikgoftar Fathi Ali Ghanbari Mitra Bakhtiari

Published in: Animal models and experimental medicine (2022)

Royal jelly upregulates the antioxidant status, inhibits the mitochondrial-dependent apoptosis pathway, and increases the rate of proliferation. This therapeutic agent effectively protected the testis against nicotine-associated damages by antioxidant and anti-apoptotic effects.

Keyphrases

oxidative stress
anti inflammatory
smoking cessation
cell death
umbilical cord
mesenchymal stem cells
signaling pathway
cell cycle arrest
endoplasmic reticulum stress
bone marrow
germ cell