Asymmetric Copper-Catalyzed Carbomagnesiation of Cyclopropenes.
Longyang DianDaniel S MüllerIlan MarekPublished in: Angewandte Chemie (International ed. in English) (2017)
The highly diastereo- and enantioselective formation of polysubstituted cyclopropanes was easily achieved through the asymmetric copper-catalyzed carbomagnesiation reaction of nonfunctionalized cyclopropene derivatives. The carbometalated species generated in situ readily undergo C-C and C-X bond-forming reactions with various electrophiles with complete retention of configuration.
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