Als3-Th-cell-epitopes plus the novel combined adjuvants of CpG, MDP, and FIA synergistically enhanced the immune response of recombinant TRAP derived from Staphylococcus aureus in mice.
Jinzhu MaWei LiuBeiyan WangSimiao YuLiquan YuBaifen SongYongzhong YuZhanbo ZhuYudong CuiPublished in: Immunity, inflammation and disease (2021)
Als3 epitopes significantly enhanced TRAP immunogenicity. ATT plus the novel combined adjuvants of CpG, MDP, and FIA induced the strong immune response and protection against S. aureus, revealing the combination of CpG, MDP, and FIA adjuvant acts the synergistic effect.