Tiotropium Add-On and Treatable Traits in Asthma-COPD Overlap: A Real-World Pilot Study.

Yoshihisa IshiuraMasaki FujimuraNoriyuki OhkuraJohsuke HaraKahori NakahamaYusuke SawaiTakeshi TamakiRyuta MuraiToshiki ShimizuNaoyuki MiyashitaShosaku Nomura

Published in: Journal of asthma and allergy (2022)

TIO add-on therapy to FP/FM in patients with ACO, considered difficult to treat because of the presence of both asthma and COPD, resulted in improvements in lung function parameters in this real-world pilot study, indicating the potential value of TIO add-on therapy as a "treatable traits" option for standard treatment for ACO.

Keyphrases

lung function
chronic obstructive pulmonary disease
cystic fibrosis
air pollution
genome wide
stem cells
gene expression
risk assessment
visible light
human health
combination therapy