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Current models to understand the onset and progression of scoliotic deformities in adolescent idiopathic scoliosis: a systematic review.

A R MeiringEsther Paula de KaterAgnita StadhouderBarend J van RoyenPaul BreedveldTheodoor H Smit
Published in: Spine deformity (2022)
This study presents a comprehensive overview of the current modeling techniques to understand the mechanics of the scoliotic deformities, predict the risk of curve progression in AIS and thereby substantiate etiopathogenetic theories. Although AIS remains to be seen as a complex and multifactorial problem, the progression of its deformity can be predicted with good accuracy. Modeling of AIS develops rapidly and may lead to the identification of risk factors and mitigation strategies in the near future. The overview presented provides a basis to follow this development.
Keyphrases
  • risk factors
  • climate change
  • bioinformatics analysis