Patterns of Treatment Failure in Primary Central Nervous System Lymphoma.
James R Janopaul-NaylorJimmy S PatelManali RupjiDavid C QianKimberly B HoangNeal S McCallAshley J SchlafsteinMadison L ShoafShawn KothariJeffrey J OlsonHui-Kuo ShuJim ZhongStewart G NeillBree EatonPublished in: American journal of clinical oncology (2024)
Our findings reaffirm the importance of systemic and intrathecal therapies for local control in PCNSL. However, bulky tumors trend to fail locally, warranting further investigation about the role of local therapies or systemic therapy intensification.