Tauroursodeoxycholic Acid Inhibits Nuclear Factor Kappa B Signaling in Gastric Epithelial Cells and Ameliorates Gastric Mucosal Damage in Mice.

Su Hwan KimJi Won KimSeong-Joon KohSang Gyun KimJeong Mo BaeJung Ho KimJeong Hwan ParkMee Soo ChangKee Don ChoiHyoun Woo KangByeong Gwan KimKook Lae Lee

Published in: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi (2022)

TUDCA inhibited NF-κB signaling in gastric epithelial cells and ameliorated ethanol- and NSAID-induced gastritis in murine models. These results support the potential of TUDCA for the prevention of gastritis in humans.

Keyphrases

nuclear factor
toll like receptor
helicobacter pylori
helicobacter pylori infection
oxidative stress
high glucose
signaling pathway
mouse model
inflammatory response
skeletal muscle
ulcerative colitis
human health