Profibrotic Circulating Proteins and Risk of Early Progressive Renal Decline in Patients With Type 2 Diabetes With and Without Albuminuria.
Katsuhito IharaJan SkupieńHiroki KobayashiZaipul I Md DomJonathan M WilsonKristina O'NeilHannah S BadgerLenden M BowsmanEiichiro SatakeMatthew D BreyerKevin L DuffinAndrzej S KrolewskiPublished in: Diabetes care (2020)
Elevation of circulating profibrotic proteins is associated with the development of early progressive renal decline in type 2 diabetes. This association is independent from albuminuria status and points to the importance of the fibrotic process in the development of early renal decline.