Automatic determination of heart rates from microscopy videos of early life stages of fish.
Raymond NepstadEmlyn DaviesDag AltinTrond NordtugBjørn Henrik HansenPublished in: Journal of toxicology and environmental health. Part A (2017)
Toxic effects of organic hydrophobic contaminants include impacts on fish heart rate (HR) and cardiac functioning. Thus, in ecotoxicology as well as aquaculture and even medicine, fish heart functioning plays an important role in application areas. The aim of this study was to assemble a pipeline of image processing and statistical techniques to extract HR information from microscopy videos of the embryo and larval stages of three species of fish (Atlantic cod, haddock, and Atlantic bluefin tuna). The method enables automatic processing for a large number of individuals, saving a significant amount of time compared with manual processing, while simultaneously eliminating the type of errors such a manual process might incur.
Keyphrases
- heart rate
- early life
- deep learning
- heart rate variability
- blood pressure
- single molecule
- heart failure
- high resolution
- machine learning
- optical coherence tomography
- high throughput
- high speed
- oxidative stress
- healthcare
- emergency department
- label free
- left ventricular
- health information
- patient safety
- zika virus
- solid phase extraction
- drosophila melanogaster
- molecularly imprinted
- tandem mass spectrometry