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Experiments on physical ablation of long bone using microwave ablation; defining optimal settings using ex- and in-vivo experiments.

Hendricus NijlandJinwen ZhuThomas KweeDingjun HaoPaul Christiaan Jutte
Published in: PloS one (2023)
Microwave ablation is technically effective for creating cell death in (sheep) long bone. It is recommended to start ablations with a slow-cooking period, gradually increasing the surrounding tissue temperature in two minutes from 40 to 90°C. Ex-vivo results cannot simply be translated to in-vivo.
Keyphrases
  • radiofrequency ablation
  • cell death
  • bone mineral density
  • soft tissue
  • bone loss
  • bone regeneration
  • physical activity
  • mental health
  • postmenopausal women
  • cell cycle arrest
  • pi k akt
  • signaling pathway