Routine diversion following delayed IPAA construction does not reduce the incidence of pouch-related sepsis or failure in patients with ulcerative colitis.

Amandeep PooniMantaj S BrarErin Diane KennedyZane CohenHelen MacRaeAnthony de Buck van Overstraeten

Published in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2024)

Pouch related sepsis and IPAA failure did not differ between modified 2-stage and 3-stage construction techniques. Among the sub-group of patients experiencing pouch related sepsis, there was no difference in failure between groups. The results suggest diverting ileostomy may be safely avoided following delayed pouch reconstruction in appropriately selected patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
intensive care unit
acute kidney injury
peritoneal dialysis
ulcerative colitis
clinical practice
drug induced