Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case.
Shahana AyubSundas SaboorSadia Suhail UsmaniSana JavedGauvain Kankeu TonpouwoSaeed AhmedPublished in: The mental health clinician (2022)
Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms after undergoing Roux-en-Y gastric bypass. The mechanism of lithium toxicity is discussed; recommendations for clinicians regarding lithium use in postsurgical patients are provided; and previous case reports of lithium toxicity post-gastric bypass surgery are analyzed. Awareness and education of lithium absorption changes postbariatric surgery is essential for optimal patient care. Close clinical and drug concentration level monitoring is warranted.
Keyphrases
- roux en y gastric bypass
- gastric bypass
- weight loss
- obese patients
- bariatric surgery
- solid state
- bipolar disorder
- oxidative stress
- minimally invasive
- end stage renal disease
- healthcare
- chronic kidney disease
- palliative care
- emergency department
- ejection fraction
- major depressive disorder
- coronary artery disease
- prognostic factors
- coronary artery bypass
- peritoneal dialysis
- depressive symptoms
- physical activity
- clinical practice
- smoking cessation
- patient reported
- patient reported outcomes