Role of the mitophagy-apoptosis axis in the pathogenesis of polycystic ovarian syndrome.

Hiroshi KobayashiHiroshi ShigetomiSho MatsubaraChiharu YoshimotoShogo Imanaka

Published in: The journal of obstetrics and gynaecology research (2024)

In conclusion, fetuses exposed to a hyperandrogenemic intrauterine environment may cause the PCOS phenotype possibly through disruption of the compensatory regulation of the mitophagy-apoptosis axis.

Keyphrases

endoplasmic reticulum stress
oxidative stress
cell cycle arrest
cell death
nlrp inflammasome
polycystic ovary syndrome
case report
gestational age
metabolic syndrome
adipose tissue
signaling pathway
preterm birth