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Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity.

Fatemeh Kazemi-LomedashtFarzad Taghizadeh-HesaryZahra FaalMahdi Behdani
Published in: Current protein & peptide science (2024)
The developed TDT-triVGB3 is potentially a novel agent for targeting VEGFR1/ VEGFR2 over-expressing cancer cells.
Keyphrases
  • vascular endothelial growth factor
  • induced apoptosis
  • escherichia coli
  • endothelial cells
  • cell cycle arrest
  • cancer therapy
  • signaling pathway
  • endoplasmic reticulum stress