Neoadjuvant Radiotherapy Versus No Radiotherapy for Stage IV Rectal Cancer: a Systematic Review and Meta-analysis.

Ryan Anthony F AgasLester Bryan A CoJ C Kennetth M JacintoKelvin Ken L YuPaolo G SogonoWarren R BacorroTeresa T Sy Ortin

Published in: Journal of gastrointestinal cancer (2019)

The current available evidence shows an LRFS benefit with NRT over no RT in patients with stage IV rectal cancer. The review also suggests a possible OS benefit with NRT, although this finding should be interpreted with caution.

Keyphrases

rectal cancer
locally advanced
squamous cell carcinoma
early stage
radiation therapy
radiation induced