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Beta-thalassemia: renal complications and mechanisms: a narrative review.

Christos DemosthenousEfthymia VlachakiChrysa ApostolouPerla EleftheriouAggeliki KotsiaftiEvangelia VetsiouEvdokia MandalaVassilios PerifanisPantelis Sarafidis
Published in: Hematology (Amsterdam, Netherlands) (2019)
Kidney disease may develop through progressive renal tubular and glomerular damage; thus, its early recognition is important in order to prevent and/or reverse deterioration. This review will provide an insight on the involved mechanisms implicated in kidney disease in thalassemic patients and will discuss the updates on diagnosis and prevention of renal complications in thalassemia.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • risk factors
  • multiple sclerosis
  • oxidative stress
  • prognostic factors
  • sickle cell disease
  • diabetic nephropathy