Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes.
Claudia CicognolaNiklas Mattsson-CarlgrenDanielle van WestenHenrik ZetterbergKaj BlennowSebastian PalmqvistKhazar AhmadiOlof StrandbergErik StomrudShorena JanelidzeOskar HanssonPublished in: Neurology (2023)
In summary, pericyte damage, reflected by CSF PDGFRβ, may be involved in age-related BBB disruption together with neuroinflammation, but is not related to Alzheimer-related pathological changes.