Computational Analysis of Pathogenetic Pathways in Alzheimer's Disease and Prediction of Potential Therapeutic Drugs.

Maria Cristina PetraliaKatia ManganoMaria Catena QuattropaniVittorio Lenzo Ferdinando Nicoletti Paolo Fagone

Published in: Brain sciences (2022)

This study aimed to integrate the transcriptional profiles associated with common familial AD mutations in neurons in order to characterize the pathogenetic mechanisms involved in AD and to find more effective drugs for AD.

Keyphrases

spinal cord
transcription factor
early onset
oxidative stress
heat shock