Gender-specific outcomes of deep brain stimulation for Parkinson's disease - results from a single movement disorder center.

Dorothee KüblerMelanie AstaloschVerena GausPatricia KrauseAna Luísa de Almeida MarcelinoGerd-Helge SchneiderAndrea Kühn

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)

STN-DBS is a highly effective treatment for motor and non-motor symptoms of PD for both women and men but our study hints towards gender-specific outcomes in non-motor-domains like cognition, depressive symptoms, and impulsivity. To explore this in more detail, larger cohorts need to be investigated in multicenter trials.

Keyphrases

deep brain stimulation
obsessive compulsive disorder
parkinson disease
depressive symptoms
mental health
clinical trial
middle aged
white matter
physical activity
insulin resistance
skeletal muscle
replacement therapy
breast cancer risk