Pathophysiology of hypereosinophilia-associated heart disease.

Usman SunusiBen ZiegelmeyerImmaculeta OsujiMario MedvedovicHaley ToddJoe Abou-KhalilNives Zimmermann

Published in: bioRxiv : the preprint server for biology (2024)

Eosinophils are required for heart damage in hypereosinophilia-associated heart disease. Additionally, myeloid cells, granulocytes and T-cell cooperatively or independently participate in the pathogenesis of hypereosinophilia-associated heart disease.

Keyphrases

pulmonary hypertension
induced apoptosis
cell cycle arrest
heart failure
oxidative stress
bone marrow
dendritic cells
atrial fibrillation
cell death
immune response
cell proliferation