First-in-human study of a novel cell death tracer [ 99m Tc]Tc-Duramycin: safety, biodistribution and radiation dosimetry in healthy volunteers.

Taco Metelerkamp CappenbergStijn De SchepperChristel VangestelStef De LombaerdeLeonie WyffelsTim Van den WyngaertJeffrey MattisBrian GrayKoon PakSigrid StroobantsFilipe Elvas

Published in: EJNMMI radiopharmacy and chemistry (2023)

NCT05177640, Registered April 30, 2021, https://clinicaltrials.gov/study/NCT05177640 .

Keyphrases

cell death
endothelial cells
signaling pathway
cell proliferation
cell cycle arrest