Treatment of rickets and dyslipidemia in twins with progressive familial intrahepatic cholestasis type 2.
Sunitha R SuraEmily L Germain-LeePublished in: International journal of pediatric endocrinology (2020)
Higher doses of Vitamin D therapy are needed for treatment of rickets secondary to cholestasis. Extremely low HDL-C levels are characteristic of PFIC and improve with treatment of underlying cholestasis. Maternal intrahepatic cholestasis during pregnancy can be an early warning sign.