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Preeclampsia Onset, Days to Delivery, and Autism Spectrum Disorders in Offspring: Clinical Birth Cohort Study.

Sarah A CarterJane C LinTing ChowMayra P MartinezChunyuan QiuR Klara FeldmanRob S McConnellAnny H Xiang
Published in: JMIR public health and surveillance (2024)
Preeclampsia during pregnancy was associated with ASD risk in children, and the risk was greater with earlier onset. However, the number of days from first preeclampsia onset to delivery was not associated with ASD risk in children. Our study suggests that ASD risk in children associated with preeclampsia is not increased by expectant management of preeclampsia in standard clinical practice. Our results emphasize the need to identify effective approaches to preventing the onset of preeclampsia, especially during early pregnancy. Further research is needed to confirm if this finding applies across different populations and clinical settings.
Keyphrases
  • autism spectrum disorder
  • early onset
  • young adults
  • attention deficit hyperactivity disorder
  • pregnancy outcomes
  • clinical practice
  • intellectual disability
  • metabolic syndrome
  • skeletal muscle