The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells.

Huang-Ju TuYi-Jyun LinMin-Wu ChaoTing-Yi SungYi-Wen WuYi-Ying ChenMei-Hsiang LinJing-Ping LiouShiow-Lin PanChia-Ron Yang

Published in: Clinical epigenetics (2018)

Collectively, our data highlighted that MPT0G211 in combination with chemotherapy drugs has significant anticancer activity, suggesting a novel strategy for the treatment of acute leukemia.

Keyphrases

induced apoptosis
endothelial cells
cell cycle arrest
electronic health record
big data
induced pluripotent stem cells
locally advanced
squamous cell carcinoma
machine learning
endoplasmic reticulum stress
signaling pathway
combination therapy
oxidative stress
cell death
pi k akt