Development of a New Folate-Derived Ga-68-Based PET Imaging Agent.

Christian BrandValerie A LongoMike GroaningWolfgang A WeberThomas Reiner

Published in: Molecular imaging and biology (2018)

We validated a new Ga-68 folate-based PET imaging agent with excellent pharmacokinetics and tumor uptake. Based on a head-to-head comparison between both tracers, [68Ga]NOTA-folate is a suitable imaging probe for the delineation of FR-positive tumors and a promising candidate for clinical translation.

Keyphrases

pet imaging
pet ct
positron emission tomography
optic nerve
high resolution
computed tomography
mass spectrometry
photodynamic therapy