Mutation screening of 17 candidate genes in a cohort of 67 probands with early-onset high myopia.

Fang Liu Junwen Wang Yiqiao Xing Tuo Li

Published in: Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) (2020)

Our research provides more evidence to support the hypothesis that mutations in ARR3, SLC39A5 and NDUFAF7 are disease-causing genes for eo-HM and broadens the eo-HM mutation spectrum among different ethnic groups. It also deepens understanding of the contributions of ARR3, SLC39A5, and NDUFAF7 to eo-HM.

Keyphrases

early onset
late onset
dna methylation