Intensity of repetitive negative thinking in depression is associated with greater functional connectivity between semantic processing and emotion regulation areas.

Aki TsuchiyagaitoStella M SánchezMasaya Misaki Rayus Kuplicki Heekyong Park Martin P Paulus Salvador M Guinjoan

Published in: Psychological medicine (2022)

RNT intensity is directly related to connectivity between STS and AI/DLPFC. This might be a mechanism underlying the role of RNT in perceptive, cognitive, speech, and emotional processing. Future investigations will need to determine whether modifying these connectivities could be a treatment target to reduce RNT.

Keyphrases

functional connectivity
resting state
high intensity
high frequency
artificial intelligence
sleep quality
machine learning
physical activity
combination therapy
multiple sclerosis