hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts.

Yifei Wang Yaqin Zhang Bing Lu Jianbo Xi Dickson Kofi Wiredu Ocansey Fei Mao Donglin Hao Yongmin Yan

Published in: Stem cells international (2023)

hucMSC-Ex alleviates DSS-induced IBD-related intestinal fibrosis by inhibiting profibrotic molecules and intestinal fibroblast proliferation and migration by decreasing ERK phosphorylation.

Keyphrases

signaling pathway
pi k akt
mouse model
high glucose
protein kinase
diabetic rats
oxidative stress
drug induced