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Tetramodal therapy with transurethral resection followed by chemoradiation in combination with hyperthermia for muscle-invasive bladder cancer: early results of a multicenter phase IIB study.

Oliver RiestererAdela AdemajEmsad PuricBrigitte EberleMarcus BeckSilvia GomezDietmar MarderEva OberackerSusanne RogersRoger A HälgThomas KernSonja SchwenneJürgen SteinEmanuel StutzOlaf TimmSebastian ZschaeckMathias S WeylandParaskevi D VeltsistaStephen WylerPeter WustStephan ScheideggerStephan BodisPirus Ghadjar
Published in: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group (2022)
Tetramodal therapy of T2-T4 MIBC is promising with excellent local response, moderate toxicity and good QoL. This study deserves continuation into the second stage.
Keyphrases
  • muscle invasive bladder cancer
  • oxidative stress
  • clinical trial
  • squamous cell carcinoma
  • stem cells
  • radiation therapy
  • rectal cancer
  • locally advanced
  • smoking cessation