Renal outcomes of diabetic patients treated with combination therapy of ACE inhibitors plus either thiazide diuretics or calcium channel blockers: comparative retrospective cohort study in Northwestern Ethiopia.
Adeladlew Kassie NetereEsmael Ali MuhammadMezgebu Silamsaw AsresMasho Tigabie TekliePublished in: BMJ open (2021)
Compared with HCT, patients on CCBs had significantly prevented risks of renal events. However, both groups appeared with the same cardiovascular events. HCT-based regimen and higher initial SBP levels were significantly associated with eGFR reductions.
Keyphrases
- cardiovascular events
- combination therapy
- end stage renal disease
- coronary artery disease
- small cell lung cancer
- ejection fraction
- angiotensin converting enzyme
- newly diagnosed
- cardiovascular disease
- chronic kidney disease
- epidermal growth factor receptor
- type diabetes
- peritoneal dialysis
- tyrosine kinase
- patient reported outcomes
- angiotensin ii
- human health
- adipose tissue
- cell cycle arrest
- risk assessment
- cell proliferation
- cell death
- insulin resistance