Molecular features and prognostic factors of locally advanced microsatellite instability-high gastric cancer.
Kenichiro FurukawaKeiichi HatakeyamaMasanori TerashimaKenichi UrakamiYusuke KosekiKeiichi FujiyaYutaka TanizawaEtsuro BandoKen YamaguchiPublished in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2024)
The molecular features and prognostic factors of locally advanced MSI-H gastric cancer were clarified. S-1 adjuvant chemotherapy appears to be beneficial, and the T cell-inflamed gene expression signature and histopathological type are prognostic factors in MSI-H tumors.