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Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis.

Zhaojie MengShuya ZhangWei LiYunzhe WangMinjie WangXin LiuCong-Lin LiuSha LiaoTianxiao LiuChongzhe YangJes S LindholtLars M RasmussenLasse M ObelJane StubbeAxel Cosmus Pyndt DiederichsenYong SunYabing ChenPaul B YuPeter LibbyGuo Ping ShiJunli Guo
Published in: European heart journal (2023)
Eosinophils release cationic proteins that can promote SMC calcification and atherogenesis using the BMPR-1A/1B-Smad-1/5/8-Runx2 signalling pathway.
Keyphrases
  • chronic kidney disease
  • pulmonary arterial hypertension
  • epithelial mesenchymal transition
  • transcription factor
  • transforming growth factor
  • signaling pathway
  • pulmonary hypertension