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Single-Cell RNA Sequencing of the Adult Mammalian Heart-State-of-the-Art and Future Perspectives.

Monika M Gladka
Published in: Current heart failure reports (2021)
The application of scRNA-seq in the cardiovascular field is continuously expanding, providing new detailed insights into cardiac pathophysiology. Increased understanding of cardiac pathophysiology on the single-cell level will contribute to the development of novel, more effective therapeutic strategies. Here, we summarise the possible application of scRNA-seq to the adult mammalian heart.
Keyphrases
  • single cell
  • rna seq
  • high throughput
  • left ventricular
  • heart failure
  • atrial fibrillation
  • childhood cancer
  • gene expression
  • dna methylation
  • young adults