Obesity and biochemical recurrence in clinically localised prostate cancer: a systematic review and meta-analysis of 86,490 patients.
Mario Rivera-IzquierdoJavier Pérez de RojasVirginia Martínez-RuizMiguel Ángel Arrabal-PoloBeatriz Perez-GomezJosé Juan Jiménez MoleónPublished in: Prostate cancer and prostatic diseases (2022)
Obesity showed a moderate, consistent relationship with biochemical recurrence after radical prostatectomy. Measurement of BMI and BCR was variable, highlighting the need for standardised clinical guidelines. Preventive weight control programs may have a role in reducing BCR for clinically localised PC patients.
Keyphrases
- radical prostatectomy
- prostate cancer
- weight gain
- weight loss
- insulin resistance
- metabolic syndrome
- acute lymphoblastic leukemia
- body mass index
- end stage renal disease
- type diabetes
- ejection fraction
- tyrosine kinase
- newly diagnosed
- public health
- physical activity
- peritoneal dialysis
- chronic myeloid leukemia
- high intensity
- patient reported outcomes
- clinical practice
- skeletal muscle
- free survival